|
KMID : 0613820000100010086
|
|
Journal of Life Science
2000 Volume.10 No. 1 p.86 ~ p.93
|
|
|
Structure and Hydrolysis Study of Inclusion Complex of Cyclodextrin and Aspirin
|
|
|
|
|
Abstract
|
|
|
|
Specific molecular recognition of cyclodextrin and aspirin was determined. A stable 1:1 inclusion complex was established in solution. The distinct structure of inclusion complex was elucidated by FT-IR, FAB-MS, UV, 1H NMR, and 13C NMR spectroscopy. Based on the 1H NMR data, a time-averaged conformation of α-cyclodextrin exhibited significant catalytic activity toward the hydrolysis of aspirin in alkaline solution.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|